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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ak8Gt(OST16378)Lex
gene trap OST16378, Lexicon Genetics
MGI:5429197
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ak8Gt(OST16378)Lex/Ak8Gt(OST16378)Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:5429555


Genotype
MGI:5429555
hm1
Allelic
Composition
Ak8Gt(OST16378)Lex/Ak8Gt(OST16378)Lex
Genetic
Background
involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ak8Gt(OST16378)Lex mutation (1 available); any Ak8 mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• no notable behavior phenotype despite hydrocephalus (J:185566)
• no notable behavior phenotype despite hydrocephalus (J:185566)

craniofacial
N
• doming of head not observed (J:185566)
• doming of head not observed (J:185566)

growth/size/body
N
• situs inversus was not observed (J:185566)
• situs inversus was not observed (J:185566)

nervous system
• mild to moderate hydrocephalus that becomes evident at approximately 2 weeks of age (late onset) and reaches maximum severity by 3 weeks of age (J:185566)
• mild to moderate hydrocephalus that becomes evident at approximately 2 weeks of age (late onset) and reaches maximum severity by 3 weeks of age (J:185566)
• mild bilateral dilation of lateral ventricles (J:185566)
• mild bilateral dilation of lateral ventricles (J:185566)
• reduced size of hippocampus (J:185566)
• reduced size of hippocampus (J:185566)

reproductive system
N
• normal fertility (J:185566)
• normal fertility (J:185566)





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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory