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Allele Symbol Allele Name Allele ID |
Tbxa2rtm1.1Bhk targeted mutation 1.1, Beverly H Koller MGI:5319073 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice exposed to ovalbumin and U-46619 fail to exhibit increased airway resistance unlike control mice
• however, mice exposed to increasing doses of thromboxane receptor agonist U-46619 exhibit dose-dependent increase in airway resistance
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice exposed to increasing doses of thromboxane receptor agonist U-46619 exhibit an attenuated dose-dependent increase in airway resistance unlike control mice
• mice exposed to U-46619 and methacholine exhibit less of an increased in airway resistance compared with control mice
• however, mice exposed ovalbumin and U-46619 exhibit dose-dependent increase in airway resistance
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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