All Phenotypes Mapt<tm1(Setdb1)Akba> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mapt^{tm1(Setdb1)Akba}
targeted mutation 1, Schahram Akbarian
MGI:5298877

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mapt^{tm1(Setdb1)Akba}/Mapt^{tm1(Setdb1)Akba}	involves: 129S7/SvEvBrd * C57BL/6J	MGI:5299158
cn2	Mapt^{tm1(Setdb1)Akba}/Mapt⁺ Mecp2^tm1Jae/Y Tg(Nes-cre)1Atp/0	involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * FVB/N	MGI:5299159
cn3	Mapt^{tm1(Setdb1)Akba}/Mapt^{tm1(Setdb1)Akba} Mecp2^tm1Jae/Y Tg(Nes-cre)1Atp/0	involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * FVB/N	MGI:5299160

Allelic Composition	Mapt^{tm1(Setdb1)Akba}/Mapt^{tm1(Setdb1)Akba}
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapt^{tm1(Setdb1)Akba} mutation (0 available); any Mapt mutation (428 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:178512 )

N	• mice exhibit normal survival

behavior/neurological

behavior/neurological phenotype ( J:178512 )

N	• mice exhibit normal neurological function

Allelic Composition	Mapt^{tm1(Setdb1)Akba}/Mapt⁺ Mecp2^tm1Jae/Y Tg(Nes-cre)1Atp/0
Genetic Background	involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapt^{tm1(Setdb1)Akba} mutation (0 available); any Mapt mutation (428 available)
Mecp2^tm1Jae mutation (2 available); any Mecp2 mutation (38 available)
Tg(Nes-cre)1Atp mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:178512 )

• most mice die between 8 weeks and 24 weeks of age

behavior/neurological

impaired coordination ( J:178512 )

Allelic Composition	Mapt^{tm1(Setdb1)Akba}/Mapt^{tm1(Setdb1)Akba} Mecp2^tm1Jae/Y Tg(Nes-cre)1Atp/0
Genetic Background	involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * FVB/N

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:178512 )

• most mice die between 8 weeks and 24 weeks of age

behavior/neurological

impaired coordination ( J:178512 )

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