Mouse Genome Informatics
hm1
    Nhlrc1tm1(KOMP)Vlcg/Nhlrc1tm1(KOMP)Vlcg
involves: C57BL/6J * C57BL/6NTac

cell line(s): 10571D-E2
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype

Lafora bodies in tissues of Nhlrc1tm1(KOMP)Vlcg/Nhlrc1tm1(KOMP)Vlcg mice

homeostasis/metabolism
• mice exhibit increased Lafora bodies and total glycogen levels in the heart muscle, skeletal muscle, and brain compared with wild-type mice
• brain glycogen levels in the insoluble pellet is increased compared to in wild-type mice
• however, no Lafora bodies are detected in the liver

muscle

Mouse Models of Human Disease
OMIM IDRef(s)
Myoclonic Epilepsy of Lafora 254780 J:165994