All Phenotypes Hmmr<tm1Baa> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Hmmr^tm1Baa
targeted mutation 1, Benjamin A Alman
MGI:2682898

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hmmr^tm1Baa/Hmmr^tm1Baa	involves: 129P2/OlaHsd * C57BL/6	MGI:2682908
cx2	Apc^tm1Rak/Apc⁺ Hmmr^tm1Baa/Hmmr^tm1Baa	involves: 129P2/OlaHsd * C57BL/6	MGI:2682909

Allelic Composition	Hmmr^tm1Baa/Hmmr^tm1Baa
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hmmr^tm1Baa mutation (0 available); any Hmmr mutation (47 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reduced fertility ( J:86065 )

• homozygous matings resulted in significantly fewer viable litters compared to either heterozygous or wild-type matings

Allelic Composition	Apc^tm1Rak/Apc⁺ Hmmr^tm1Baa/Hmmr^tm1Baa
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apc^tm1Rak mutation (1 available); any Apc mutation (154 available)
Hmmr^tm1Baa mutation (0 available); any Hmmr mutation (47 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

decreased tumor incidence ( J:86065 )

• decreased number of aggressive fibromatosis tumors formed relative to Apc^tm1Rak heterozygotes

• the number of gastrointestinal polyps was not altered relative to Apc^tm1Rak heterozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23