About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tyr+
wild type
MGI:2432472
Summary 8 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Tyrc-26DVT/Tyr+ involves: 101/Rl * C3H/Rl * T-stock MGI:5293748
ht2
 		Tyrc-ch83R/Tyr+ involves: 101/Rl * C3H/Rl * T-stock MGI:5294374
ht3
 		Tyrc-25H/Tyr+ involves: AKR * STOCK Tyrc-25H/Tyrc-ch MGI:3691584
ht4
 		Tyrc-25H/Tyr+ involves: SM/J * STOCK Tyrc-h/Tyrc-25H MGI:3691849
cx5
 		Tyrc-ch/Del(7)Tyrc-3H involves: 101/H * C3H/HeH MGI:4431256
cx6
 		Tyrc/Del(7)Tyrc-3H involves: 101/H * C3H/HeH MGI:4431254
cx7
 		Tyrc-ch/Del(7)Tyrc-6H involves: 101/H * C3H/HeH MGI:4843178
cx8
 		Tenm4l7Rn3-4R/Tyrc-26DVT involves: 101/Rl * BALB/cRl * C3H/Rl * C57BL/10Rl * T-stock MGI:3789295


Genotype
MGI:5293748
ht1
Allelic
Composition		 Tyrc-26DVT/Tyr+
Genetic
Background		 involves: 101/Rl * C3H/Rl * T-stock
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-26DVT mutation (2 available); any Tyr mutation (375 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:5294374
ht2
Allelic
Composition		 Tyrc-ch83R/Tyr+
Genetic
Background		 involves: 101/Rl * C3H/Rl * T-stock
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-ch83R mutation (0 available); any Tyr mutation (375 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:100221 )
• appears wild-type




Genotype
MGI:3691584
ht3
Allelic
Composition		 Tyrc-25H/Tyr+
Genetic
Background		 involves: AKR * STOCK Tyrc-25H/Tyrc-ch
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-25H mutation (0 available); any Tyr mutation (375 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal chromosome morphology ( J:5520 )
• this allele includes a deletion, detected in banded mitotic chromosomes, comprising 1-6cM, representing about 7.6% of Chr 7




Genotype
MGI:3691849
ht4
Allelic
Composition		 Tyrc-25H/Tyr+
Genetic
Background		 involves: SM/J * STOCK Tyrc-h/Tyrc-25H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc-25H mutation (0 available); any Tyr mutation (375 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
induced chromosome breakage ( J:5437 )
• an induced, associated deletion involves, minimally, the MOD2 structural locus




Genotype
MGI:4431256
cx5
Allelic
Composition		 Tyrc-ch/Del(7)Tyrc-3H
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7)Tyrc-3H mutation (0 available); any Del(7)Tyrc-3H mutation (0 available)
Tyrc-ch mutation (79 available); any Tyr mutation (375 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
diluted coat color ( J:5063 )
• the coat color is intermediate between that expected for an albino mouse and a mouse homozygous for chinchilla

integument
diluted coat color ( J:5063 )
• the coat color is intermediate between that expected for an albino mouse and a mouse homozygous for chinchilla




Genotype
MGI:4431254
cx6
Allelic
Composition		 Tyrc/Del(7)Tyrc-3H
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7)Tyrc-3H mutation (0 available); any Del(7)Tyrc-3H mutation (0 available)
Tyrc mutation (79 available); any Tyr mutation (375 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
absent coat pigmentation ( J:5063 )
• this mouse is albino

integument
absent coat pigmentation ( J:5063 )
• this mouse is albino




Genotype
MGI:4843178
cx7
Allelic
Composition		 Tyrc-ch/Del(7)Tyrc-6H
Genetic
Background		 involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7)Tyrc-6H mutation (1 available); any Del(7)Tyrc-6H mutation (0 available)
Tyrc-ch mutation (79 available); any Tyr mutation (375 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
diluted coat color ( J:5741 )
• these mice are noticeably lighter in color than mice that are homozygous chinchilla

integument
diluted coat color ( J:5741 )
• these mice are noticeably lighter in color than mice that are homozygous chinchilla




Genotype
MGI:3789295
cx8
Allelic
Composition		 Tenm4l7Rn3-4R/Tyrc-26DVT
Genetic
Background		 involves: 101/Rl * BALB/cRl * C3H/Rl * C57BL/10Rl * T-stock
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tenm4l7Rn3-4R mutation (0 available); any Tenm4 mutation (302 available)
Tyrc-26DVT mutation (2 available); any Tyr mutation (375 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:96673 )
N
• when the Odz4l7Rn3-4R allele is inherited from the father, animals survive to adulthood
prenatal lethality, complete penetrance ( J:96673 )
• when the Odz4l7Rn3-4R allele is inherited from the mother, animals die as embryos between E8.5 and E17.5

cardiovascular system
abnormal vasculogenesis ( J:96673 )
• when the Odz4l7Rn3-4R allele is inherited from the mother, defects in vascularization are seen

embryo
embryonic growth retardation ( J:96673 )
• when the Odz4l7Rn3-4R allele is inherited from the mother, developmental delay is seen
abnormal limb bud morphology ( J:96673 )
• when the Odz4l7Rn3-4R allele is inherited from the mother, abnormalities in limb bud elongation are seen
kinked neural tube ( J:96673 )
• when the Odz4l7Rn3-4R allele is inherited from the mother, kinky neural tubes are observed

growth/size/body
embryonic growth retardation ( J:96673 )
• when the Odz4l7Rn3-4R allele is inherited from the mother, developmental delay is seen
decreased body size ( J:96673 )
• when the Odz4l7Rn3-4R allele is inherited from the father, 30% of animals appear runted and scruffy at weaning

limbs/digits/tail
abnormal limb bud morphology ( J:96673 )
• when the Odz4l7Rn3-4R allele is inherited from the mother, abnormalities in limb bud elongation are seen

nervous system
kinked neural tube ( J:96673 )
• when the Odz4l7Rn3-4R allele is inherited from the mother, kinky neural tubes are observed

skeleton
thoracic vertebral fusion ( J:96673 )
• when the Odz4l7Rn3-4R allele is inherited from the father, 27% of mutant animals display lumbar and/or thoracic vertebral fusions
abnormal cervical axis morphology ( J:96673 )
• when the Odz4l7Rn3-4R allele is inherited from the father, an aberrant spinous process is observed in 18% of mutant animals
lumbar vertebral fusion ( J:96673 )
• when the Odz4l7Rn3-4R allele is inherited from the father, 27% of mutant animals display lumbar and/or thoracic vertebral fusions




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory