Hoxd^{tm19.1(Hoxb1)Ddu}
Targeted Allele Detail

Summary

• Symbol: Hoxd^{tm19.1(Hoxb1)Ddu}
• Name: homeobox D cluster; targeted mutation 19.1, Denis Duboule
• MGI ID: MGI:7639889
• Synonyms: TgH[b1/lac/Del7]Ge
• Gene: Hoxd Location: unknown Genetic Position: Chr2, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:70547
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Hoxd^{tm19.1(Hoxb1)Ddu} involves 5 genes/genome features (Hoxd13, Hoxd12, Hoxd11 ...) View all
• Hoxd^{tm19.1(Hoxb1)Ddu} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Hoxb1 (MGI:96182)

• Mutation details: The targeting construct inserted Hoxb1/lac/loxP reporter gene inserted 5' of Hoxd13, replacing Hoxd13 through hoxd4. Cre-mediated recombination removed the selection cassette. (J:70547)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxd Mutation: 0 strains or lines available

References

• Original: J:70547 Zakany J, et al., Localized and transient transcription of Hox genes suggests a link between patterning and the segmentation clock. Cell. 2001 Jul 27;106(2):207-17
• All: 1 reference(s)