Tg(UCP2,UCP3)#Chw
Transgene Detail

Summary

• Symbol: Tg(UCP2,UCP3)#Chw
• Name: transgene insertion, Craig Warden
• MGI ID: MGI:7280671
• Transgene: Tg(UCP2,UCP3)#Chw Location: unknown
• Alliance: Tg(UCP2,UCP3)#Chw page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(UCP2,UCP3)#Chw expresses 2 genes
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  UCP2 (7351)

  Ucp2	(MGI:109354)

  human

  UCP3 (7352)

  Ucp3	(MGI:1099787)

• Mutation details: An 80 kb human BAC clone containing the UCP2 and UCP3 genes and promoters to produce transgenic mice that slightly overexpress UCP2 and 3. Multiple lines were created. (J:82916)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:82916 Horvath TL, et al., Uncoupling proteins-2 and 3 influence obesity and inflammation in transgenic mice. Int J Obes Relat Metab Disord. 2003 Apr;27(4):433-42
• All: 7 reference(s)