Ncoa4^tm1Msnt
Targeted Allele Detail

Summary

• Symbol: Ncoa4^tm1Msnt
• Name: nuclear receptor coactivator 4; targeted mutation 1, Massimo Santoro
• MGI ID: MGI:5660201
• Gene: Ncoa4 Location: Chr14:31881884-31901210 bp, + strand Genetic Position: Chr14, 19.4 cM, cytoband B
• Alliance: Ncoa4^tm1Msnt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215322
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 2-7 were replaced with a neo cassette via homologous recombination. (J:215322)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ncoa4 Mutation: 76 strains or lines available

References

• Original: J:215322 Bellelli R, et al., NCOA4 transcriptional coactivator inhibits activation of DNA replication origins. Mol Cell. 2014 Jul 3;55(1):123-37
• All: 4 reference(s)