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Ephb1tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Ephb1tm1Dgen
Name: Eph receptor B1; targeted mutation 1, Deltagen
MGI ID: MGI:5659739
Synonyms: Ephb1-
Gene: Ephb1  Location: Chr9:101922128-102354693 bp, - strand  Genetic Position: Chr9, 54.15 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:214959
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA Lac0-SA-IRES-lacZ-neo/kan cassette was inserted replacing 100 bp of genomic sequence in exon 8 via homologous recombination. Western blot analysis confirmed the absence of protein in brain lysates from P1 homozygous mutant mice. (J:214959)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ephb1 Mutation:  3 strains or lines available
References
Original:  J:214959 Lodato S, et al., Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Nat Neurosci. 2014 Aug;17(8):1046-54
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory