Wwtr1tm1.1Eno
Targeted Allele Detail
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Symbol: |
Wwtr1tm1.1Eno |
Name: |
WW domain containing transcription regulator 1; targeted mutation 1.1, Eric N Olson |
MGI ID: |
MGI:5544289 |
Synonyms: |
Tazfl, TazloxP |
Gene: |
Wwtr1 Location: Chr3:57363070-57483331 bp, - strand Genetic Position: Chr3, 27.74 cM
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Alliance: |
Wwtr1tm1.1Eno page
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Cardiomyopathy in Wwtr1tm1.2Eno/Wwtr1+ Yap1tm1.1Eno/Yap1tm1.1Eno Tg(Myh6-cre)2182Mds/0 mice
Show the 3 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:200670
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S/SvEv
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 3 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3. Flp mediated recombination removed the neo cassette.
(J:200670)
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Generation of the Wwtr1tm1.1Eno and Wwtr1tm1.2Eno alleles |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Wwtr1 Mutation: |
23 strains or lines available
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Original: |
J:200670 Xin M, et al., Hippo pathway effector Yap promotes cardiac regeneration. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13839-44 |
All: |
78 reference(s) |
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