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| Caption | Generation of the Wwtr1tm1.1Eno (TazloxP) and Wwtr1tm1.2Eno (Tazfloxed) alleles. (A) Schematic representation of the mouse Wwtr1 (Taz) locus and the targeting strategy. Positions of Southern blot probes and locations of restriction enzyme sites are indicated. Homologous recombination in ES cells and recombinase-mediated excisions generated the Wwtr1 floxed allele, in which exon 3 is replaced by one loxP site. Genotyping primers are designated TF, TR1, and TR2. DTA, diptheria toxin A; E, exon; FRT, FLP recombinase target; HI, BamHI; neo, neomycin resistance cassette. | ||||||
| Copyright | This image is from Xin M, Proc Natl Acad Sci U S A 2013 Aug 20;110(34):13839-44. Copyright 2013 National Academy of Sciences, U.S.A. J:200670 | ||||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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