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Tg(Guca1a*L151F/EGFP)#Wbae
Transgene Detail
Nomenclature
Symbol: Tg(Guca1a*L151F/EGFP)#Wbae
Name: transgene insertion, Wolfgang Baehr
MGI ID: MGI:5523963
Synonyms: G1(L151F)-GFP
Transgene: Tg(Guca1a*L151F/EGFP)#Wbae  Location: unknown  
Slowly progressive photoreceptor degeneration in Tg(Guca1a*L151F/EGFP)#Wbae/0 and Tg(Guca1a*L151F)#Wbae/0 mice

Show the 1 phenotype image(s) involving this allele.

Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Tg(Guca1a*L151F/EGFP)#Wbae expresses 1 gene
 
Mutation detailsThis transgene expresses mouse Guca1a with a C to T point mutation in codon 151 (L151F) fused to a C-terminal EGFP under the control of endogenous regulatory elements. Expression is localized to the photoreceptor inner and outer segments. One line was created and the pound symbol (#) is used when the line is not specified. (J:199392)
Schematic of the Tg(Guca1a*L151F)#Wbae and Tg(Guca1a*L151F/EGFP)#Wbae transgenes
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:199392 Jiang L, et al., RNAi-mediated gene suppression in a GCAP1(L151F) cone-rod dystrophy mouse model. PLoS One. 2013;8(3):e57676
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory