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Transgene Detail
Symbol: Tg(Guca1a*L151F)#Wbae
Name: transgene insertion, Wolfgang Baehr
MGI ID: MGI:5523961
Synonyms: G1(L151F)
Transgene: Tg(Guca1a*L151F)#Wbae  Location: unknown  
Slowly progressive photoreceptor degeneration in Tg(Guca1a*L151F/EGFP)#Wbae/0 and Tg(Guca1a*L151F)#Wbae/0 mice

Show the 1 phenotype image(s) involving this allele.

Strain of Origin:  FVB/N
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
Tg(Guca1a*L151F)#Wbae expresses 1 gene
Mutation detailsThis transgene expresses mouse Guca1a with a C to T point mutation in codon 151 (L151F) under the control of endogenous regulatory elements. Expression is localized to the photoreceptor inner and outer segments, with stronger expression in the cones than rods. One line was created and the pound symbol (#) is used when the line is not specified. (J:199392)
Schematic of the Tg(Guca1a*L151F)#Wbae and Tg(Guca1a*L151F/EGFP)#Wbae transgenes
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:199392 Jiang L, et al., RNAi-mediated gene suppression in a GCAP1(L151F) cone-rod dystrophy mouse model. PLoS One. 2013;8(3):e57676
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
The Jackson Laboratory