Nuak1^tm1Esu
Targeted Allele Detail

Summary

• Symbol: Nuak1^tm1Esu
• Name: NUAK family, SNF1-like kinase, 1; targeted mutation 1, Hiroyasu Esumi
• MGI ID: MGI:5428915
• Synonyms: Nuak1^flox
• Gene: Nuak1 Location: Chr10:84206769-84276461 bp, - strand Genetic Position: Chr10, 41.42 cM
• Alliance: Nuak1^tm1Esu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185463
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 3 is flanked with loxP sites. (J:185463)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nuak1 Mutation: 43 strains or lines available

References

• Original: J:185463 Inazuka F, et al., Muscle-specific knock-out of NUAK family SNF1-like kinase 1 (NUAK1) prevents high fat diet-induced glucose intolerance. J Biol Chem. 2012 May 11;287(20):16379-89
• All: 2 reference(s)