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Targeted Allele Detail
Symbol: Del(14Trim13-Rnaseh2b)6Rdf
Name: deletion, Chr 14, Riccardo Dalla-Favera 6
MGI ID: MGI:5304666
Synonyms: CDR-, Del6Rdf
Gene: Del(14Trim13-Rnaseh2b)6Rdf  Location: Chr14:61835696-62610441 bp  Genetic Position: Chr14, Syntenic
Germline Transmission:  Earliest citation of germline transmission: J:179879
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Intergenic deletion, Intragenic deletion
  Del(14Trim13-Rnaseh2b)6Rdf involves 16 genes/genome features (Gm27845, Gm27747, Gm27928 ...) View all
Mutation detailsFlp-mediated recombination removed the 800 kb region between Trim13 and Rnaseh2b flanked by Is(14)1Rdf and Is(14)5Rdf, respectively, as well as the EGFP. This deletion removes Trim13, Kcnrg, Dleu2, Gm20034, Mir16-1, Mir15a, Mir1196, Dleu7, and Rnaseh2b. (J:179879)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(14Trim13-Rnaseh2b)6Rdf Mutation:  0 strains or lines available
Original:  J:179879 Lia M, et al., Functional dissection of the chromosome 13q14 tumor-suppressor locus using transgenic mouse lines. Blood. 2012 Mar 29;119(13):2981-90
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.19
The Jackson Laboratory