Summary | Mutation origin | Mutation description | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Is(14)1Rdf
Name:	insertion, Chr 14, Riccardo Dalla-Favera 1
MGI ID:	MGI:4437012
Gene:	Is(14)1Rdf  Location: unknown  Genetic Position: Chr14, Syntenic

Germline Transmission:	Earliest citation of germline transmission: J:156946
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: LoxP and FRT sites as well as a Neo cassette and EGFP coding sequence were placed approximately 20 kb centromeric to Trim13 by homologous recombination. (J:156946)

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Is(14)1Rdf

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Is(14)1Rdf Mutation:	0 strains or lines available

Original:	J:156946 Klein U, et al., The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia. Cancer Cell. 2010 Jan 19;17(1):28-40
All:	2 reference(s)