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Mpzl2tm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Mpzl2tm1Lex
Name: myelin protein zero-like 2; targeted mutation 1, Lexicon Pharmaceuticals
MGI ID: MGI:5007250
Gene: Mpzl2  Location: Chr9:45042425-45054015 bp, + strand  Genetic Position: Chr9, 24.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171883
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThe Mpzl2 gene consists of 6 exons, with the start codon located in exon 1 (NCBI accession NM_007962.2). Exons 1 through 3 were targeted by homologous recombination. Disruption of the target gene was confirmed by Southern hybridization analysis. (J:171883)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Mpzl2 Mutation:  7 strains or lines available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory