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Targeted Allele Detail
Symbol: Osr1tm2.1Jian
Name: odd-skipped related transcription factor 1; targeted mutation 2.2, Rulang Jiang
MGI ID: MGI:5003112
Synonyms: Osr1deltaE2
Gene: Osr1  Location: Chr12:9574442-9581500 bp, + strand  Genetic Position: Chr12, 4.05 cM
Dilated epicardium, hemorrhaging, and edema in Osr1tm2.1Jian/Osr1tm2.1Jian embryos

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:171478
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Cre-mediated recombination removed exon 2. Homozygous mice recapitulate the phenotype of null mice. (J:171478)
Generation of the Osr1tm2Jian, Osr1tm2.1Jian, and Osr1tm2.2Jian alleles
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Osr1 Mutation:  12 strains or lines available
Original:  J:171478 Gao Y, et al., The zinc finger transcription factors Osr1 and Osr2 control synovial joint formation. Dev Biol. 2011 Apr 1;352(1):83-91
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory