Ccr5^tm2Blck
Targeted Allele Detail

Summary

• Symbol: Ccr5^tm2Blck
• Name: C-C motif chemokine receptor 5; targeted mutation 2, Bruno Luckow
• MGI ID: MGI:4360353
• Gene: Ccr5 Location: Chr9:123921557-123934153 bp, + strand Genetic Position: Chr9, 75.05 cM, cytoband F
• Alliance: Ccr5^tm2Blck page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152815
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutation: Insertion The coding region was replaced with DsRed2 and a floxed hygro cassette. (J:152815)

Generation of the Ccr5^tm2Blck allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccr5 Mutation: 29 strains or lines available

Notes

This allele was originally generated in ES cells containing Ccr2^tm1Blck.

References

• Original: J:152815 Luckow B, et al., Microinjection of Cre recombinase protein into zygotes enables specific deletion of two eukaryotic selection cassettes and enhances the expression of a DsRed2 reporter gene in Ccr2/Ccr5 double-deficient mice. Genesis. 2009 Aug;47(8):545-58
• All: 1 reference(s)