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Nqo1tm1Msho
Targeted Allele Detail
Nomenclature
Symbol: Nqo1tm1Msho
Name: NAD(P)H dehydrogenase, quinone 1; targeted mutation 1, Minho Shong
MGI ID: MGI:4353051
Gene: Nqo1  Location: Chr8:107388225-107403206 bp, - strand  Genetic Position: Chr8, 54.08 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:151045
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 3425 bp fragment including exons 5 and 6 was replaced with a pgk-neo cassette via homologous recombination. (J:151045)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nqo1 Mutation:  13 strains or lines available
References
Original:  J:151045 Hwang JH, et al., Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice. Diabetes. 2009 Apr;58(4):965-74
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory