All Phenotypes Nqo1<tm1Msho> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nqo1^tm1Msho
targeted mutation 1, Minho Shong
MGI:4353051

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nqo1^tm1Msho/Nqo1^tm1Msho	involves: 129S4/SvJae * C57BL/6	MGI:4353052

Allelic Composition	Nqo1^tm1Msho/Nqo1^tm1Msho
Genetic Background	involves: 129S4/SvJae * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nqo1^tm1Msho mutation (0 available); any Nqo1 mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal cell physiology ( J:151045 )

• absence of beta-lapachone induced phosphorylations of AMP activated protein kinase and acetyl-CoA carboxylase in MEFs, unlike in heterozygous MEFs

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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