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Camk2dtm1.2Eno
Targeted Allele Detail
Nomenclature
Symbol: Camk2dtm1.2Eno
Name: calcium/calmodulin-dependent protein kinase II, delta; targeted mutation 1.2, Eric N Olson
MGI ID: MGI:3837728
Synonyms: CaMKIIdelta-
Gene: Camk2d  Location: Chr3:126596302-126846326 bp, + strand  Genetic Position: Chr3, 55.97 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:146285
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEvBrd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination was used to remove exons 1 and 2. The absence of protein expression was confirmed by western blot analysis on cardiac extracts. (J:146285)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Camk2d Mutation:  19 strains or lines available
References
Original:  J:146285 Backs J, et al., The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2342-7
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory