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Sox5tm2.1Vlf
Targeted Allele Detail
Nomenclature
Symbol: Sox5tm2.1Vlf
Name: SRY (sex determining region Y)-box 5; targeted mutation 2.1, Veronique Lefebvre
MGI ID: MGI:3799355
Synonyms: Sox5fl-
Gene: Sox5  Location: Chr6:143828425-144781977 bp, - strand  Genetic Position: Chr6, 76.14 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:137217
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsGerm line, cre-mediated recombination was used to remove exon CE5. The absence of the long form of Sox5 was confirmed by western blot analysis on chondrocyte extracts. (J:137217)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox5 Mutation:  22 strains or lines available
References
Original:  J:137217 Dy P, et al., Generation of mice harboring a Sox5 conditional null allele. Genesis. 2008 Jun;46(6):294-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory