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Thap11tm1Tpz
Targeted Allele Detail
Nomenclature
Symbol: Thap11tm1Tpz
Name: THAP domain containing 11; targeted mutation 1, Thomas P Zwaka
MGI ID: MGI:3797582
Synonyms: Roninflox
Gene: Thap11  Location: Chr8:106581764-106583582 bp, + strand  Genetic Position: Chr8, 53.05 cM, cytoband D2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136306
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of the coding region and an frt-flanked neo cassette with a 5' loxP site was inserted downstream of the coding region. (J:136306)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 26 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Thap11 Mutation:  7 strains or lines available
References
Original:  J:136306 Dejosez M, et al., Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells. Cell. 2008 Jun 27;133(7):1162-74
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory