Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Thap11tm1Tpz mutation
(0 available);
any
Thap11 mutation
(9 available)
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cellular
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• cre-transfected ES cells show an apparent high rate of apoptosis and no homozygous recombined sub-clones are found
• however, cre-transduced MEFs from E14.5 embryos show nearly 100% recombination
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
E2f1Tg(Wnt1-cre)2Sor mutation
(2 available);
any
E2f1 mutation
(25 available)
Thap11tm1Tpz mutation
(0 available);
any
Thap11 mutation
(9 available)
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craniofacial
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• mice show almost complete agenesis of the neural crest-derived craniofacial skeleton
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
E2f1Tg(Wnt1-cre)2Sor mutation
(2 available);
any
E2f1 mutation
(25 available)
Thap11em1Poche mutation
(0 available);
any
Thap11 mutation
(9 available)
Thap11tm1Tpz mutation
(0 available);
any
Thap11 mutation
(9 available)
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integument
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• 2 out of 5 mice exhibit white belly spots
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limbs/digits/tail
pigmentation
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• 2 out of 5 mice exhibit white belly spots
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Prrx1-cre)1Cjt mutation
(2 available)
Thap11tm1Tpz mutation
(0 available);
any
Thap11 mutation
(9 available)
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craniofacial
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• mice show a dramatic loss of mesoderm-derived bones in the skull
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