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Mirc1tm1.1Tyj
Targeted Allele Detail
Nomenclature
Symbol: Mirc1tm1.1Tyj
Name: microRNA cluster 1, including Mir17 through Mir92-1; targeted mutation 1.1, Tyler Jacks
MGI ID: MGI:3793628
Synonyms: miR17~92fl, Mir17-92tm1.1Tyj
Gene: Mirc1  Location: Chr14:115281103-115281938 bp  Genetic Position: Chr14, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:134861
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe Frt-flanked neomycin cassette in Mir17-92tm1Tyj was removed through Flp-mediated excision. (J:134861)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 259895 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mirc1 Mutation:  6 strains or lines available
References
Original:  J:134861 Ventura A, et al., Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell. 2008 Mar 7;132(5):875-86
All:  54 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory