Actb^tm2.1Npa
Targeted Allele Detail

Summary

• Symbol: Actb^tm2.1Npa
• Name: actin, beta; targeted mutation 2.1, Novartis Pharma AG
• MGI ID: MGI:3769439
• Synonyms: FRT/Credel
• Gene: Actb Location: Chr5:142888870-142892509 bp, - strand Genetic Position: Chr5, 81.8 cM
• Alliance: Actb^tm2.1Npa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:129105
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: BALB/c

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Intragenic deletion
• Mutation details: Actb^tm2Npa mice were crossed with a cre-deleter strain to remove the floxed stop codon upstream of the EGFP reporter gene. Strong EGFP expression was observed in numerous tissues including brain, heart and kidney. (J:129105)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Actb Mutation: 55 strains or lines available

References

• Original: J:129105 Jagle U, et al., Conditional transgene expression mediated by the mouse beta-actin locus. Genesis. 2007 Nov;45(11):659-66
• All: 1 reference(s)