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Tcra-Jtm3.1Krg
Targeted Allele Detail
Summary
Symbol: Tcra-Jtm3.1Krg
Name: T cell receptor alpha, joining region; targeted mutation 3.1, Michael S Krangel
MGI ID: MGI:3767247
Synonyms: Tcra-Jtm3Krg, Tcratm3Krg, TEA-T
Gene: Tcra-J  Location: unknown  Genetic Position: Chr14, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:128344
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Not Applicable)
Mutation:    Insertion
 
Mutation detailsA transcriptional terminator and a loxP site flanked neomycin resistance gene cassette were inserted downstream of the TEA (T early alpha) exon. The neo cassette was subsequently removed by cre-mediated recombination. (J:128344)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcra-J Mutation:  0 strains or lines available
References
Original:  J:128344 Abarrategui I, et al., Noncoding transcription controls downstream promoters to regulate T-cell receptor alpha recombination. EMBO J. 2007 Oct 17;26(20):4380-90
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory