Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
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hematopoietic system
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• 5' Jalpha segment rearrangments are dramatically reduced to the levels seen in Tcratm1Krg
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immune system
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• 5' Jalpha segment rearrangments are dramatically reduced to the levels seen in Tcratm1Krg
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rorctm1Litt mutation
(1 available);
any
Rorc mutation
(42 available)
Tcra-Jtm3.1Krg mutation
(0 available);
any
Tcra-J mutation
(0 available)
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hematopoietic system
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• unlike in Rorctm1Litt homozygotes, primary rearrangement of 5' Jalpha segments is completely abolished (0.5% compared to 54% in Rorctm1Litt homozygotes) while rearrangement of the central Jalpha segments is increased (54.8% compared to 18.2% in Rorctm1Litt homozygotes)
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immune system
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• unlike in Rorctm1Litt homozygotes, primary rearrangement of 5' Jalpha segments is completely abolished (0.5% compared to 54% in Rorctm1Litt homozygotes) while rearrangement of the central Jalpha segments is increased (54.8% compared to 18.2% in Rorctm1Litt homozygotes)
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