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Arid4atm1Alb
Targeted Allele Detail
Nomenclature
Symbol: Arid4atm1Alb
Name: AT rich interactive domain 4A (RBP1-like); targeted mutation 1, Arthur L Beaudet
MGI ID: MGI:3687004
Synonyms: Arid4a-
Gene: Arid4a  Location: Chr12:71015990-71098592 bp, + strand  Genetic Position: Chr12, 29.39 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:113402
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA vector was designed to insert a lacZ and a floxed neo into the ATG in exon 1, and replacing exon 2. RT-PCR failed to detect normal transcript in mutant mice. (J:113402)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arid4a Mutation:  42 strains or lines available
References
Original:  J:113402 Wu MY, et al., Deficiency of Rbbp1/Arid4a and Rbbp1l1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain. Genes Dev. 2006 Oct 15;20(20):2859-70
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/16/2018
MGI 6.12
The Jackson Laboratory