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S1pr2tm1Rlp
Targeted Allele Detail
Nomenclature
Symbol: S1pr2tm1Rlp
Name: sphingosine-1-phosphate receptor 2; targeted mutation 1, Richard L Proia
MGI ID: MGI:3620009
Synonyms: S1p2-, S1P2-, S1pr2-
Gene: S1pr2  Location: Chr9:20877248-20888089 bp, - strand  Genetic Position: Chr9, 7.68 cM
Hemorrhage in S1pr2tm1Rlp/S1pr2tm1Rlp S1pr3tm1Rlp/S1pr3tm1Rlp embryos

Show the 8 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:106055
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 9 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any S1pr2 Mutation:  45 strains or lines available
References
Original:  J:106055 Kono M, et al., The sphingosine-1-phosphate receptors S1P1, S1P2, and S1P3 function coordinately during embryonic angiogenesis. J Biol Chem. 2004 Jul 9;279(28):29367-73
All:  36 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory