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Phenotype Image Detail
Image
Caption A: Control littermate S1pr2tm1Rlp/S1pr2+ S1pr3tm1Rlp/S1pr3tm1Rlp (S1P 2+/- S1P 3-/-) embryo at E13.5. B: S1pr2tm1Rlp/S1pr2tm1Rlp S1pr3tm1Rlp/S1pr3tm1Rlp (S1P 1-/- S1P 3-/-) double homozygous mutant embryo at E13.5. C: Double homozygous mutant embryo at E14.5. D: Double homozygous mutant embryo at E15.5.
Copyright This image is from Kono M, J Biol Chem 2004 Jul 9;279(28):29367-73 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:106055
Associated
Alleles
Symbol Name
S1pr2tm1Rlp sphingosine-1-phosphate receptor 2; targeted mutation 1, Richard L Proia
S1pr3tm1Rlp sphingosine-1-phosphate receptor 3; targeted mutation 1, Richard L Proia
Associated
Genotypes
Allelic Composition Genetic Background
S1pr3tm1Rlp/S1pr3tm1Rlp
S1pr2tm1Rlp/S1pr2tm1Rlp 		involves: 129S6/SvEvTac * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory