Del(2Hoxd10-Hoxd12)19Ddu
Targeted Allele Detail

Summary

• Symbol: Del(2Hoxd10-Hoxd12)19Ddu
• Name: deletion, Chr 2, Denis Duboule 19
• MGI ID: MGI:3616539
• Synonyms: Del(10-12), Del19Ddu
• Gene: Del(2Hoxd10-Hoxd12)19Ddu Location: Chr2:74505357-74525449 bp Genetic Position: Chr2, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:105255
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Intergenic deletion, Intragenic deletion
• Del(2Hoxd10-Hoxd12)19Ddu involves 3 genes/genome features (Hoxd12, Hoxd11, Hoxd10) View all
• Mutation details: Produced by targeted meiotic recombination in a cross between Hoxd and Hoxd in the presence of Tg(Sycp1-cre)4Min. Hoxd10, Hoxd11, and Hoxd12, are all deleted from the Hoxd cluster. (J:105255)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(2Hoxd10-Hoxd12)19Ddu Mutation: 0 strains or lines available

References

• Original: J:105255 Tarchini B, et al., Control of Hoxd genes' collinearity during early limb development. Dev Cell. 2006 Jan;10(1):93-103
• All: 6 reference(s)