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Slc22a12tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Slc22a12tm1Dgen
Name: solute carrier family 22 (organic anion/cation transporter), member 12; targeted mutation 1, Deltagen
MGI ID: MGI:3604569
Gene: Slc22a12  Location: Chr19:6535845-6543019 bp, - strand  Genetic Position: Chr19, 5.05 cM, cytoband A
Mutation
origin
Mutant Cell Line:  3905
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details70 bp of exon 3 was replaced with a lacZ-neo cassette followed by transcription and translation STOP sequences. The absence of transcript was confirmed by northern blot analysis on kidney extracts. This is a null allele and a reporter allele. While RT-PCR analysis detects a gene transcript in kidney, testis and prostate gland, beta-galactosidase expression from this allele is detectable in brain, retina, kidney and testis. (J:101679, J:136005)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 56 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc22a12 Mutation:  13 strains or lines available
Notes
See also, data as provided by Deltagen, Inc.
References
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory