About   Help   FAQ
Targeted Allele Detail
Symbol: Slc22a12tm1Dgen
Name: solute carrier family 22 (organic anion/cation transporter), member 12; targeted mutation 1, Deltagen
MGI ID: MGI:3604569
Gene: Slc22a12  Location: Chr19:6585875-6593062 bp, - strand  Genetic Position: Chr19, 5.05 cM, cytoband A
Alliance: Slc22a12tm1Dgen page
Mutant Cell Line:  3905
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation details70 bp of exon 3 was replaced with a lacZ-neo cassette followed by transcription and translation STOP sequences. The absence of transcript was confirmed by northern blot analysis on kidney extracts. This is a null allele and a reporter allele. While RT-PCR analysis detects a gene transcript in kidney, testis and prostate gland, beta-galactosidase expression from this allele is detectable in brain, retina, kidney and testis. (J:101679, J:136005)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 56 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc22a12 Mutation:  18 strains or lines available
See also, data as provided by Deltagen, Inc.
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Copyright, and Privacy Statement
Send questions and comments to User Support.
last database update
MGI 6.22
The Jackson Laboratory