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Targeted Allele Detail
Symbol: Rbp2tm1Eli
Name: retinol binding protein 2, cellular; targeted mutation 1, Ellen Li
MGI ID: MGI:2672086
Synonyms: CRBP II-, CRBPII-
Gene: Rbp2  Location: Chr9:98486115-98509781 bp, + strand  Genetic Position: Chr9, 51.37 cM
Germline Transmission:  Earliest citation of germline transmission: J:79282
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 1 was replaced with a neomycin selection cassette inserted by homologous recombination. Protein was undetected by Western blot analysis of liver and intestinal extracts obtained from homozygous mutant mice. Absence of protein was further confirmed by immunohistochemical staining of the intestinal mucosa. (J:79282)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rbp2 Mutation:  1 strain or line available
Original:  J:79282 E X, et al., Increased neonatal mortality in mice lacking cellular retinol-binding protein II. J Biol Chem. 2002 Sep 27;277(39):36617-23
All:  4 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.06
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