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Wnt3tm1Amc
Targeted Allele Detail
Nomenclature
Symbol: Wnt3tm1Amc
Name: wingless-type MMTV integration site family, member 3; targeted mutation 1, Andrew P McMahon
MGI ID: MGI:2450902
Synonyms: Wnt3n/n
Gene: Wnt3  Location: Chr11:103774150-103817957 bp, + strand  Genetic Position: Chr11, 67.5 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:81795
Parent Cell Line:  CC1.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    The gene was disrupted by insertion of an MC1neo cassette into exon 4 via homologous recombination. (J:81795)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wnt3 Mutation:  17 strains or lines available
References
Original:  J:81795 Barrow JR, et al., Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes Dev. 2003 Feb 1;17(3):394-409
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory