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Rxfp2tm1Aia
Targeted Allele Detail
Nomenclature
Symbol: Rxfp2tm1Aia
Name: relaxin/insulin-like family peptide receptor 2; targeted mutation 1, Alexander I Agoulnik
MGI ID: MGI:2388129
Synonyms: Greatko
Gene: Rxfp2  Location: Chr5:150018675-150082184 bp, + strand  Genetic Position: Chr5, 89.23 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79124
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Duplication, Insertion
  Rxfp2tm1Aia involves 1 genes/genome features (Rxfp2) View all
 
Mutation detailsGene targeting resulted in the duplication of exons 12-16 and the insertion of vector sequence into the 16 intron of the endogenous gene. (J:79124)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rxfp2 Mutation:  31 strains or lines available
References
Original:  J:79124 Gorlov IP, et al., Mutations of the GREAT gene cause cryptorchidism. Hum Mol Genet. 2002 Sep 15;11(19):2309-18
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory