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Targeted Allele Detail
Symbol: Gria2tm1.1Phs
Name: glutamate receptor, ionotropic, AMPA2 (alpha 2); targeted mutation 1.1, Peter H Seeburg
MGI ID: MGI:2178125
Synonyms: GluR-BR, Gria2R
Gene: Gria2  Location: Chr3:80681450-80802835 bp, - strand  Genetic Position: Chr3, 35.5 cM
Germline Transmission:  Earliest citation of germline transmission: J:50929
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted
Mutations:    Insertion, Intragenic deletion
Mutation detailsThis heritable allele is a derivative of Gria2tm1Phs in which the loxP flanked neomycin cassette was removed by crossing mice carrying this allele to mice carrying the Tg(CMV-Cre)1Cgn transgene. A single loxP site in intron 11 remained in place of the neomycin cassette. (J:50929)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gria2 Mutation:  46 strains or lines available
Original:  J:50929 Kask K, et al., The AMPA receptor subunit GluR-B in its Q/R site-unedited form is not essential for brain development and function. Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13777-82
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory