About   Help   FAQ
Spontaneous Allele Detail
Symbol: Tyrcm1OR
Name: tyrosinase; albino mottling 1, Oak Ridge
MGI ID: MGI:2153728
Synonyms: cm1OR, Tyrc-1R
Gene: Tyr  Location: Chr7:87424771-87493512 bp, - strand  Genetic Position: Chr7, 49.01 cM
Strain of Origin:  C3H/Rl
Allele Type:    Spontaneous (Hypomorph)
Mutation:    Transposon insertion
Mutation detailsThe mutation is a 5.4kb intracisternal A particle (IAP) element insertion upstream of the promoter. This is a hypomorphic allele; Northern blot analysis and RT-PCR results show that expression is at much lower levels in homozygous than in wild-type mice. (J:38209)
Inheritance:    Recessive
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tyr Mutation:  366 strains or lines available
Original:  J:38209 Wu M, et al., Inherited somatic mosaicism caused by an intracisternal A particle insertion in the mouse tyrosinase gene. Proc Natl Acad Sci U S A. 1997 Feb 4;94(3):890-4
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.03
The Jackson Laboratory