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Aldh1a2tm1Ipc
Targeted Allele Detail
Nomenclature
Symbol: Aldh1a2tm1Ipc
Name: aldehyde dehydrogenase family 1, subfamily A2; targeted mutation 1, Pierre Chambon
MGI ID: MGI:1857891
Synonyms: Raldh2-
Gene: Aldh1a2  Location: Chr9:71215789-71296243 bp, + strand  Genetic Position: Chr9, 39.85 cM
Abnormal development of laryngeal and tracheal cartilages in Aldh1a2tm1Dll/Aldh1a2tm1Ipc and Aldh1a2tm1Dll/Aldh1a2tm1Dll mice and absence of thymus and parathyroid glands in Aldh1a2tm1Dll/Aldh1a2tm1Ipc mice

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:54067
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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Disease models
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Expression
In Mice Carrying this Mutation: 139 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aldh1a2 Mutation:  0 strains or lines available
References
Original:  J:54067 Niederreither K, et al., Embryonic retinoic acid synthesis is essential for early mouse post-implantation development [see comments]. Nat Genet. 1999 Apr;21(4):444-8
All:  37 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory