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| Caption | A-C: Comparison of the laryngeal and tracheal cartilages of E18.5 wild type (WT, A) Aldh1a2tm1Dll/Aldh1a2tm1Ipc (neo/-, B) and Aldh1a2tm1Dll/Aldh1a2tm1Dll (neo/neo, C) mice. Alizarin red-alcian blue staining. D and E: Hyoid and thyroid carliages of wild type and Aldh1a2tm1Dll/Aldh1a2tm1Ipc mice, respectively. An ectopic cartilage connects these two elements in the mutant (bracket). F and G: Profile views of the cricoid cartilage and first tracheal ring of wild type and Aldh1a2tm1Dll/Aldh1a2tm1Ipc mice, respectively. The posterior aspect of this cartilage is abnormally segmented in the mutant (arrows). H and I: Coronal sections through the upper mediastinum of wild type and Aldh1a2tm1Dll/Aldh1a2tm1Ipc newborn mice, respectively, showing the absence of thymus (Tm) in the mutant (asterisks). At, atria (J and K) Sections through the lateral portions of the thyroid gland (Ty) of wild type and Aldh1a2tm1Dll/Aldh1a2tm1Ipc newborn mice, respectively, showing a lack of parathyroid glands (Pty) in the mutant; tetrachrome staining. | ||||||
| Copyright | This image is from Vermot J, Proc Natl Acad Sci U S A 2003 Feb 18;100(4):1763-8. Copyright 2003 National Academy of Sciences, U.S.A. J:81969 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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