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Grid2Lc-J
Spontaneous Allele Detail
Nomenclature
Symbol: Grid2Lc-J
Name: glutamate receptor, ionotropic, delta 2; lurcher Jackson
MGI ID: MGI:1857346
Synonyms: lc
Gene: Grid2  Location: Chr6:63232860-64681307 bp, + strand  Genetic Position: Chr6, 29.77 cM
Pyknotic Purkinjie cells in Grid2Lc-J/Grid2+ mouse cerebellum

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  BALB/cByJ
Mutation
description
Allele Type:    Spontaneous
Mutation:    Nucleotide substitutions
 
Mutation detailsThis allele comprises a nucleotide substitution that causes a change in an amino acid in the third transmembrane domain of Grid2. (J:42431)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Grid2 Mutation:  59 strains or lines available
References
Original:  J:42385 De Jager PL, et al., A new allele of the lurcher gene, lurcherJ. Mamm Genome. 1997 Sep;8(9):647-50
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory