Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Magel2tm1.1Mus
Name:	MAGE family member L2; targeted mutation 1.1, Francoise Muscatelli
MGI ID:	MGI:4849506
Gene:	Magel2  Location: Chr7:62026758-62031388 bp, + strand  Genetic Position: Chr7, 34.37 cM
Alliance:	Magel2tm1.1Mus page

Germline Transmission:	Earliest citation of germline transmission: J:166548
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The 5' portion of the coding region was replaced with a floxed hygro cassette. Cre-mediated recombination removed the hygro cassette. The absence of expression in the brain was confirmed by immunohistochemistry. (J:166548)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	11 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Magel2 Mutation:	58 strains or lines available

Original:	J:166548 Schaller F, et al., A single postnatal injection of oxytocin rescues the lethal feeding behaviour in mouse newborns deficient for the imprinted Magel2 gene. Hum Mol Genet. 2010 Dec 15;19(24):4895-905
All:	5 reference(s)