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Kctd21 Gene Detail
Summary
  • Symbol
    Kctd21
  • Name
    potassium channel tetramerisation domain containing 21
  • Synonyms
    EG622320
  • Feature Type
    protein coding gene
  • IDs
    MGI:3643121
    NCBI Gene: 622320
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:96981534-96999420 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 53.47 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    176 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3643121
 protein coding gene Chr7:96981515-96999423 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032521
 protein coding gene Chr7:100013375-100032751 (+)
A/J MGP_AJ_G0032495
 protein coding gene Chr7:97534812-97557748 (+)
AKR/J MGP_AKRJ_G0032431
 protein coding gene Chr7:99847425-99869129 (+)
BALB/cJ MGP_BALBcJ_G0032506
 protein coding gene Chr7:97228283-97246584 (+)
C3H/HeJ MGP_C3HHeJ_G0032221
 protein coding gene Chr7:100215502-100237279 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033004
 protein coding gene Chr7:103909141-103929161 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029999
 protein coding gene Chr7:99997739-100015648 (+)
CAST/EiJ MGP_CASTEiJ_G0031548
 protein coding gene Chr7:91726842-91747373 (+)
CBA/J MGP_CBAJ_G0032188
 protein coding gene Chr7:107421631-107439366 (+)
DBA/2J MGP_DBA2J_G0032340
 protein coding gene Chr7:95903188-95922189 (+)
FVB/NJ MGP_FVBNJ_G0032296
 protein coding gene Chr7:95682257-95700156 (+)
LP/J MGP_LPJ_G0032429
 protein coding gene Chr7:101337993-101357929 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032329
 protein coding gene Chr7:108964248-108983712 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033026
 protein coding gene Chr7:99151642-99169399 (+)
PWK/PhJ MGP_PWKPhJ_G0031266
 protein coding gene Chr7:88957247-88975245 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031109
 protein coding gene Chr7:86386682-86404419 (+)
WSB/EiJ MGP_WSBEiJ_G0031665
 protein coding gene Chr7:99787715-99807365 (+)



Homology
more
  • Human Ortholog
    KCTD21, potassium channel tetramerization domain containing 21
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KCTD21, potassium channel tetramerization domain containing 21
  • Synonyms
    KCASH2
  • Links
    NCBI Gene ID: 283219
    neXtProt AC: NX_Q4G0X4
    UniProt: Q4G0X4

  • Chr Location
    11q14.1; chr11:78171249-78188626 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044952 Ensembl Gene Model | MGI Sequence Detail 17887 C57BL/6J ±  kb
transcript ENSMUST00000054107 Ensembl | MGI Sequence Detail 2966 Not Applicable  
polypeptide ENSMUSP00000051316 Ensembl | MGI Sequence Detail 260 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000032411 BTB/POZ domain-containing protein KCTD21
    (term hierarchy)
  • InterPro Domains
    IPR000210 BTB/POZ domain
    IPR045763 BTB/POZ domain-containing protein KCTD11/21, C-terminal domain
    IPR003131 Potassium channel tetramerisation-type BTB domain
    IPR011333 SKP1/BTB/POZ domain superfamily
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 1
References
more
  • Summaries
    All 43
    Gene Ontology 4
    Phenotypes 26
  • Earliest
    J:141526 Russell LB, et al., Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals. Genetics. 1979 May;92(1):205-13
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory