Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nfe2l3tm1Vbl
Name:	nuclear factor, erythroid derived 2, like 3; targeted mutation 1, Volker Blank
MGI ID:	MGI:3045075
Synonyms:	Nrf3-
Gene:	Nfe2l3  Location: Chr6:51409650-51435748 bp, + strand  Genetic Position: Chr6, 24.84 cM
Alliance:	Nfe2l3tm1Vbl page

Germline Transmission:	Earliest citation of germline transmission: J:89893
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Two exons were replaced with a floxed neomycin-cytosine deamidase cassette. Transcripts lacked CNC homology, DNA binding, and leucine zipper domains. (J:89893)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfe2l3 Mutation:	28 strains or lines available

Original:	J:89893 Derjuga A, et al., Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus. Mol Cell Biol. 2004 Apr;24(8):3286-94
All:	4 reference(s)