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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nfe2l3tm1Vbl
targeted mutation 1, Volker Blank
MGI:3045075
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nfe2l3tm1Vbl/Nfe2l3tm1Vbl either: 129S6/SvEvTac or (involves: 129S6/SvEvTac * C57BL/6J) MGI:3045076
cx2
 		Nfe2l2tm1Ney/Nfe2l2tm1Ney
Nfe2l3tm1Vbl/Nfe2l3tm1Vbl 		involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J MGI:3045077
cx3
 		Nfe2tm1Sho/Nfe2tm1Sho
Nfe2l3tm1Vbl/Nfe2l3tm1Vbl 		involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J MGI:3045078


Genotype
MGI:3045076
hm1
Allelic
Composition		 Nfe2l3tm1Vbl/Nfe2l3tm1Vbl
Genetic
Background		 either: 129S6/SvEvTac or (involves: 129S6/SvEvTac * C57BL/6J)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nfe2l3tm1Vbl mutation (0 available); any Nfe2l3 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:89893 )
• life span, gross anatomy, blood parameters, and immune system were all normal




Genotype
MGI:3045077
cx2
Allelic
Composition		 Nfe2l2tm1Ney/Nfe2l2tm1Ney
Nfe2l3tm1Vbl/Nfe2l3tm1Vbl
Genetic
Background		 involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nfe2l2tm1Ney mutation (0 available); any Nfe2l2 mutation (94 available)
Nfe2l3tm1Vbl mutation (0 available); any Nfe2l3 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Genotype
MGI:3045078
cx3
Allelic
Composition		 Nfe2tm1Sho/Nfe2tm1Sho
Nfe2l3tm1Vbl/Nfe2l3tm1Vbl
Genetic
Background		 involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nfe2l3tm1Vbl mutation (0 available); any Nfe2l3 mutation (26 available)
Nfe2tm1Sho mutation (1 available); any Nfe2 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality ( J:89893 )
• reduced survival to adulthood but some did survive




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory