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Syndig1l Gene Detail
Summary
  • Symbol
    Syndig1l
  • Name
    synapse differentiation inducing 1 like
  • Synonyms
    capucin, LOC238321, SynDIG2, Tmem90a
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685107
    NCBI Gene: 627191
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:84724051-84745605 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 39.33 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    79 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685107
 protein coding gene Chr12:84724051-84745720 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019943
 protein coding gene Chr12:85406556-85428050 (-)
A/J MGP_AJ_G0019900
 protein coding gene Chr12:82174596-82196104 (-)
AKR/J MGP_AKRJ_G0019876
 protein coding gene Chr12:84397900-84419461 (-)
BALB/cJ MGP_BALBcJ_G0019880
 protein coding gene Chr12:82505775-82527338 (-)
C3H/HeJ MGP_C3HHeJ_G0019686
 protein coding gene Chr12:84869559-84893104 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020331
 protein coding gene Chr12:87875408-87903650 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017949
 protein coding gene Chr12:79065391-79087032 (-)
CAST/EiJ MGP_CASTEiJ_G0019235
 protein coding gene Chr12:79832870-79857769 (-)
CBA/J MGP_CBAJ_G0019657
 protein coding gene Chr12:91262690-91284203 (-)
DBA/2J MGP_DBA2J_G0019772
 protein coding gene Chr12:81696489-81719621 (-)
FVB/NJ MGP_FVBNJ_G0019758
 protein coding gene Chr12:80652829-80674716 (-)
LP/J MGP_LPJ_G0019844
 protein coding gene Chr12:85288732-85311407 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019797
 protein coding gene Chr12:94157933-94179820 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020365
 protein coding gene Chr12:84003152-84027361 (-)
PWK/PhJ MGP_PWKPhJ_G0018999
 protein coding gene Chr12:76185982-76208583 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018794
 protein coding gene Chr12:78484200-78505822 (-)
WSB/EiJ MGP_WSBEiJ_G0019287
 protein coding gene Chr12:84715783-84739019 (-)



Homology
more
  • Human Ortholog
    SYNDIG1L, synapse differentiation inducing 1 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SYNDIG1L, synapse differentiation inducing 1 like
  • Synonyms
    CAPUCIN, DSPC1, IFITMD4, SynDIG2, TMEM90A
  • Links
    NCBI Gene ID: 646658
    neXtProt AC: NX_A6NDD5
    UniProt: A6NDD5

  • Chr Location
    14q24.3; chr14:74405894-74480143 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    6
  • Genomic Mutations
    1 involving Syndig1l
  • Find Mice (IMSR)
    14 strains or lines available
Mice homozygous for a knock-out allele are viable and fertile, exhibit normal brain anatomy, and show no alterations in striatal vulnerability to a mutant huntingtin fragment.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    731
  • Tissues
    10
  • cDNA Data
    7
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000071234 Ensembl Gene Model | MGI Sequence Detail 21555 C57BL/6J ±  kb
transcript ENSMUST00000095550 Ensembl | MGI Sequence Detail 2524 Not Applicable  
polypeptide ENSMUSP00000093206 Ensembl | MGI Sequence Detail 237 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory