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Slc17a3 Gene Detail
Summary
  • Symbol
    Slc17a3
  • Name
    solute carrier family 17 (sodium phosphate), member 3
  • Synonyms
    Npt4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2389216
    NCBI Gene: 105355
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:24023417-24044699 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 9.95 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    273 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2389216
 protein coding gene Chr13:24020905-24044701 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020370
 protein coding gene Chr13:21286550-21310032 (+)
A/J MGP_AJ_G0020319
 protein coding gene Chr13:20893231-20915393 (+)
AKR/J MGP_AKRJ_G0020299
 protein coding gene Chr13:21147219-21168530 (+)
BALB/cJ MGP_BALBcJ_G0020317
 protein coding gene Chr13:20893139-20908796 (+)
C3H/HeJ MGP_C3HHeJ_G0020121
 protein coding gene Chr13:21223390-21239075 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020754
 protein coding gene Chr13:22067759-22089036 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018342
 protein coding gene Chr13:19668861-19692903 (+)
CAST/EiJ MGP_CASTEiJ_G0019638
 protein coding gene Chr13:20904525-20926971 (+)
CBA/J MGP_CBAJ_G0020075
 protein coding gene Chr13:22927002-22942677 (+)
DBA/2J MGP_DBA2J_G0020201
 protein coding gene Chr13:20424320-20440004 (+)
FVB/NJ MGP_FVBNJ_G0020185
 protein coding gene Chr13:20072511-20093808 (+)
LP/J MGP_LPJ_G0020274
 protein coding gene Chr13:21598738-21614334 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020212
 protein coding gene Chr13:23216229-23237460 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020796
 protein coding gene Chr13:21002335-21020941 (+)
PWK/PhJ MGP_PWKPhJ_G0019392
 protein coding gene Chr13:20454368-20475858 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019209
 protein coding gene Chr13:19810439-19832294 (+)
WSB/EiJ MGP_WSBEiJ_G0019698
 protein coding gene Chr13:21141043-21163054 (+)



Homology
more
  • Human Ortholog
    SLC17A3, solute carrier family 17 member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC17A3, solute carrier family 17 member 3
  • Synonyms
    GOUT4, NPT4, UAQTL4
  • Links
    NCBI Gene ID: 10786
    neXtProt AC: NX_O00476
    UniProt: O00476

  • Chr Location
    6p22.2; chr6:25833066-25882286 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SLC17A3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    782
  • Tissues
    62
  • cDNA Data
    56
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036083 Ensembl Gene Model | MGI Sequence Detail 21283 C57BL/6J ±  kb
transcript ENSMUST00000166467 Ensembl | MGI Sequence Detail 4336 Not Applicable  
polypeptide ENSMUSP00000131308 Ensembl | MGI Sequence Detail 498 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR011701 Major facilitator superfamily
    IPR020846 Major facilitator superfamily domain
    IPR036259 MFS transporter superfamily
    IPR017373 Sodium-dependent phosphate transport protein 4 , predicted
Molecular
Reagents
less
  • All nucleic 56
    cDNA 56

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145426
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 13
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory