Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	F2rl1tm1Cgh
Name:	F2R like trypsin receptor 1; targeted mutation 1, Shaun R Coughlin
MGI ID:	MGI:2179844
Synonyms:	F2rl1tm1Kley, PAR-2-, PAR2-
Gene:	F2rl1  Location: Chr13:95648240-95661735 bp, - strand  Genetic Position: Chr13, 49.53 cM
Alliance:	F2rl1tm1Cgh page

Germline Transmission:	Earliest citation of germline transmission: J:76626
Parent Cell Line:	RF8 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 2 was replaced with a neomycin resistance cassette via homologous recombination. Homozygous mutant animals were identified by Southern blot analysis. (J:76626)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	9 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any F2rl1 Mutation:	58 strains or lines available

Original:	J:76626 Lindner JR, et al., Delayed onset of inflammation in protease-activated receptor-2-deficient mice. J Immunol. 2000 Dec 1;165(11):6504-10
All:	31 reference(s)